Five notorious but uncaptured American serial killers are highlighted. West Mesa Bone Collector: Unidentified killer of 11 women/teens (+ unborn child) found in Albuquerque desert (2009); victims mostly had drug/sex work ties. The Doodler: Targeted gay men in San Francisco (1974-75), stabbing 6-16 victims. Killer, an aspiring cartoonist, remains unknown; a suspect was interviewed in 1976. Jeff Davis 8 Killer: Eight women, often linked to drugs/sex work, found murdered in Louisiana bayous (2005-09). Case unsolved despite person of interest Frankie Richard. Freeway Phantom: Abducted, raped, and strangled six Black girls in Washington D.C. (1972), taunting police with a note. Killer unidentified. New Bedford Highway Killer: Responsible for 9 missing/murdered female sex workers in Massachusetts (1988), bodies found along highways. Case remains unsolved with no convictions. These cases exemplify unsolved horrors overshadowed by more famous serial killers.